THE METABOLISM OF [4-14C]PREGNENOLONE BY BOAR ADRENAL AND TESTIS TISSUE IN VITRO By D. B. GOWER
نویسنده
چکیده
1. The metabolism of [4-14C]pregnenolone in vitro by boar adrenocortical and testis tissue has been studied. 2. Boar testis tissue formed three labelled A16e steroids, 5a-androst1 6-en-3oa-ol, 5a-androst1 6-en-3,B-ol and androsta-4, 16-dien3-one. In adrenal tissue very much smaller yields of the same metabolites were obtained. 3. Both tissues produced labelledprogesterone, androst-4-ene-3,17-dione and testosterone in varying quantities. The amount of progesterone was about 120 times greater in the adrenal tissue. In testis tissue dehydroepiandrosterone
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